Table 2.
son-1(sy549) enhances lin-17(n698) phenotypes to lin-17 null-like mutations
|
Genotype
|
Phenotypes
|
||||
|---|---|---|---|---|---|
| lin-17 | son-1 | bivulvaa | hermaphrodite gonadb | P12.p → P11.pc | abnormal phasmidsd |
| + | sy549 | 2% (n = 108) | 1% (n = 108) | 0 (n = 100) | 4% (n = 53) |
| n698 | + | 2% (n = 46) | 8% (n = 46) | 0 (n = 100) | 73% (n = 346) |
| n698 | sy549 | 58% (n = 98) | 28% (n = 101) | 0 (n = 100) | 98% (n = 57) |
| n671 | + | 64% (n = 66) | 23% (n = 66) | 29%e (n = 41) | 95%f (n = 400) |
| n671 | sy549 | 64% (n = 76) | 20% (n = 69) | 22% (n = 92) | N.D. |
a
Bivulva phenotype is defined as two vulval invaginations at mid- to late L4 stage.
b
Hermaphrodite gonad defect is defined as abnormal gonad morphology, single gonadal arm, and ectopic meiosis at L4 stage.
c
P11/P12 phenotype is scored by the nuclear morphologies and positions of P11.p and P12.pa cells at L4 stage.
d
L3 and L4 stage worms were tested by DiO filling of amphids and phasmids, as described by Herman and Horvitz (1994). Animals that showed positive for amphid filling and negative for phasmid filling were scored as phasmid defective. (N.D.) Not determined.
e
Data from Jiang and Sternberg (1998).
f
Data from Sawa et al. (1996).