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The differential expression patterns of 27 of the 78 serine proteases encoded in the S. mansoni genome. Seventeen were up-regulated in the germ ball, of which 10 encoded cercarial elastases, expressed 10–65-fold higher than in the day 3 schistosomulum. Eleven serine proteases were enriched in the cercaria, and five in the schistosomulum. The study reveals a wider range of cercarial elastases potentially involved in skin invasion than hitherto reported.
