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. 2011 Aug 30;6(8):e24090. doi: 10.1371/journal.pone.0024090

Table 2. Association of EPO levels with descriptive parameters in the clinical groups.

Variables Crude analysis Adjusted analysis a (n = 149)
Proportional difference 95% CI p-value Proportionaldifference 95% CI p-value
Group (n = 179)
SM 1 1
HM 0.39 0.21–0.74 0.004 0.92 0.57–1.49 0.730
UM 0.13 0.07–0.24 <0.001 1.18 0.68–2.03 0.550
IBI 0.32 0.16–0.62 0.001 0.68 0.39–1.18 0.169
Age (n = 179) b 0.99 0.97–1 0.151 1 0.99–1.01 0.890
Sex (n = 179)
Male 1 1
Female 0.99 0.59–1.66 0.972 1.17 0.83–1.65 0.355
Days of fever prior to visit/admission (n = 162) b 1.22 1.03–1.44 0.020 1.02 0.91–1.13 0.777
Hemoglobin (n = 173) b 0.93 0.93–0.94 <0.001 0.93 0.92–0.94 <0.001
Severe malnutrition (n = 159)
No 1 1
Yes 2.08 0.83–5.20 0.115 1.08 0.58–2 0.815
Lactic acidosis (n = 67)
No 1 NA c
Yes 0.87 0.37–2.07 0.754 NA NA NA
Oxygen saturation (n = 67)
≥94% 1 NA
90-<94% 2.12 0.71–6.31 0.173 NA NA NA
<90% 1.17 0.44–3.09 0.743 NA NA NA
HIV (n = 43)
No 1 NA
Yes 1.70 0.6–4.83 0.307 NA NA NA
Malaria parasites (n = 179) b 1 0.99–1 0.217 NA NA NA
a

The analysis was done adjusting by age, sex, malnutrition, hemoglobin and days of fever prior to visit/admission.

b

Proportional increment per unit. Age in months, hemoglobin in g/dl and malaria parasites in asexual parasites/µl.

c

NA: Not applicable.

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