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. 2011 Aug 31;6(8):e24037. doi: 10.1371/journal.pone.0024037

Table 1. Baseline factors associated with incident HIV infection among HIV-uninfected partners in HIV discordant couples, Masaka, Uganda.

N (%) Seroconverters PYO Rate/ 100 PYO RR (95% CI) LRT p-value aRR (95% CI)
Total 482 (100.0) 34 786.6 4.3
Male circumcision
Circumcised 93 (19.3) 3 152.5 2.0 1.0 0.21 1.0
Uncircumcised 237 (49.2) 20 386.4 5.2 2.6 (0.8-8.9) 1.6 (0.4-5.7)
Female 152 (31.5) 11 247.7 4.4 2.3 (0.6-8.1) 1.3 (0.3-4.9)
Age group
≥35 260 (53.9) 11 447.9 2.5 1.0 0.01 1.0
25-34 175 (36.3) 16 269.1 5.9 2.4 (1.1-5.2) 2.7 (1.2-5.8)
18-24 47 (9.8) 7 69.6 10.1 4.1 (1.6-10.7) 4.1 (1.6-10.8)
Marital status
Married 396 (82.2) 25 646.5 3.9 1.0 0.21
Steady partner 86 (17.8) 9 140.1 6.4 1.7 (0.8-3.6)
Religious affiliation
Non Muslim 383 (79.5) 30 622.6 4.8 1.0 0.16
Muslim 99 (20.5) 4 164.0 2.4 0.5 (0.2-1.4)
Education level
≥Secondary 94 (19.5) 6 151.4 4.0 1.0 0.93
Primary 338 (70.1) 25 555.2 4.5 1.1 (0.5-2.8)
None 50 (10.4) 3 80.1 3.7 0.9 (0.2-3.8)
Alcohol use
No 213 (44.2) 8 350.3 2.3 1.0 0.01 1.0
Yes 269 (55.8) 26 436.3 6.0 2.6 (1.2-5.8) 2.6 (1.1-6.0)
Extramarital sex in past year
No 310 (64.3) 21 511.3 4.1 1.0 0.69
Yes 172 (35.7) 13 275.4 4.7 1.1 (0.6-2.3)
Condom use frequency in past year
Did not use 193 (40.0) 23 308.2 7.5 1.0 0.001 1.0
Sometimes 210 (43.6) 10 344.3 2.9 0.4 (0.2-0.8) 0.4 (0.2-0.8)
Always 79 (16.4) 1 134.2 0.7 0.1 (0.01-0.7) 0.1 (0.02-0.9)
Genital ulcer disease in past year
No 354 (73.4) 22 585.6 3.8 1.0 0.21
Yes 128 (26.6) 12 201.0 6.0 1.6 (0.8-3.2)
Genital discharge in the past year
No 378 (78.4) 19 626.4 3.0 1.0 0.002 1.0
Yes 104 (21.6) 15 160.2 9.4 3.1 (1.6-6.1) 3.4 (1.6-7.2)
Serological syphilis
Negative 457 (94.8) 31 745.9 4.2 1.0 0.37
Positive 25 (5.2) 3 40.7 7.4 1.8 (0.5-5.9)
Receipt of ART by HIV-infected partner
Yes 80 (16.6) 3 138.6 2.2 1.0 0.33
No 359 (74.5) 29 612.9 4.7 2.2 (0.7-7.2)
Data not collected 43 (8.9) 2 35.1 5.7 2.6 (0.4-15.8)

PYO, person-years of observation; RR, unadjusted rate ratio; aRR, adjusted rate ratio (All factors were adjusted for gender, age group at study entry, male circumcision, alcohol use, condom use frequency, and genital discharge in the past year); CI, confidence interval; LRT, likelihood ratio test.