Table 1. Baseline factors associated with incident HIV infection among HIV-uninfected partners in HIV discordant couples, Masaka, Uganda.
N (%) | Seroconverters | PYO | Rate/ 100 PYO | RR (95% CI) | LRT p-value | aRR (95% CI) | |
Total | 482 (100.0) | 34 | 786.6 | 4.3 | |||
Male circumcision | |||||||
Circumcised | 93 (19.3) | 3 | 152.5 | 2.0 | 1.0 | 0.21 | 1.0 |
Uncircumcised | 237 (49.2) | 20 | 386.4 | 5.2 | 2.6 (0.8-8.9) | 1.6 (0.4-5.7) | |
Female | 152 (31.5) | 11 | 247.7 | 4.4 | 2.3 (0.6-8.1) | 1.3 (0.3-4.9) | |
Age group | |||||||
≥35 | 260 (53.9) | 11 | 447.9 | 2.5 | 1.0 | 0.01 | 1.0 |
25-34 | 175 (36.3) | 16 | 269.1 | 5.9 | 2.4 (1.1-5.2) | 2.7 (1.2-5.8) | |
18-24 | 47 (9.8) | 7 | 69.6 | 10.1 | 4.1 (1.6-10.7) | 4.1 (1.6-10.8) | |
Marital status | |||||||
Married | 396 (82.2) | 25 | 646.5 | 3.9 | 1.0 | 0.21 | |
Steady partner | 86 (17.8) | 9 | 140.1 | 6.4 | 1.7 (0.8-3.6) | ||
Religious affiliation | |||||||
Non Muslim | 383 (79.5) | 30 | 622.6 | 4.8 | 1.0 | 0.16 | |
Muslim | 99 (20.5) | 4 | 164.0 | 2.4 | 0.5 (0.2-1.4) | ||
Education level | |||||||
≥Secondary | 94 (19.5) | 6 | 151.4 | 4.0 | 1.0 | 0.93 | |
Primary | 338 (70.1) | 25 | 555.2 | 4.5 | 1.1 (0.5-2.8) | ||
None | 50 (10.4) | 3 | 80.1 | 3.7 | 0.9 (0.2-3.8) | ||
Alcohol use | |||||||
No | 213 (44.2) | 8 | 350.3 | 2.3 | 1.0 | 0.01 | 1.0 |
Yes | 269 (55.8) | 26 | 436.3 | 6.0 | 2.6 (1.2-5.8) | 2.6 (1.1-6.0) | |
Extramarital sex in past year | |||||||
No | 310 (64.3) | 21 | 511.3 | 4.1 | 1.0 | 0.69 | |
Yes | 172 (35.7) | 13 | 275.4 | 4.7 | 1.1 (0.6-2.3) | ||
Condom use frequency in past year | |||||||
Did not use | 193 (40.0) | 23 | 308.2 | 7.5 | 1.0 | 0.001 | 1.0 |
Sometimes | 210 (43.6) | 10 | 344.3 | 2.9 | 0.4 (0.2-0.8) | 0.4 (0.2-0.8) | |
Always | 79 (16.4) | 1 | 134.2 | 0.7 | 0.1 (0.01-0.7) | 0.1 (0.02-0.9) | |
Genital ulcer disease in past year | |||||||
No | 354 (73.4) | 22 | 585.6 | 3.8 | 1.0 | 0.21 | |
Yes | 128 (26.6) | 12 | 201.0 | 6.0 | 1.6 (0.8-3.2) | ||
Genital discharge in the past year | |||||||
No | 378 (78.4) | 19 | 626.4 | 3.0 | 1.0 | 0.002 | 1.0 |
Yes | 104 (21.6) | 15 | 160.2 | 9.4 | 3.1 (1.6-6.1) | 3.4 (1.6-7.2) | |
Serological syphilis | |||||||
Negative | 457 (94.8) | 31 | 745.9 | 4.2 | 1.0 | 0.37 | |
Positive | 25 (5.2) | 3 | 40.7 | 7.4 | 1.8 (0.5-5.9) | ||
Receipt of ART by HIV-infected partner | |||||||
Yes | 80 (16.6) | 3 | 138.6 | 2.2 | 1.0 | 0.33 | |
No | 359 (74.5) | 29 | 612.9 | 4.7 | 2.2 (0.7-7.2) | ||
Data not collected | 43 (8.9) | 2 | 35.1 | 5.7 | 2.6 (0.4-15.8) |
PYO, person-years of observation; RR, unadjusted rate ratio; aRR, adjusted rate ratio (All factors were adjusted for gender, age group at study entry, male circumcision, alcohol use, condom use frequency, and genital discharge in the past year); CI, confidence interval; LRT, likelihood ratio test.