Table 2. Risk factors for incident HIV infection during follow up among HIV-uninfected partners in HIV discordant couples, Masaka, Uganda.
| N (%) | Seroconverters | PYO | Rate/100 PYO | RR (95% CI) | LRT p-value | aRR (95% CI) | |
| Total | 482 (100.0) | 34 | 786.6 | 4.3 | |||
| Male circumcision | |||||||
| Circumcised | 94 (19.5) | 3 | 154.3 | 1.9 | 1.0 | 0.20 | 1.0 |
| Uncircumcised | 236 (49.0) | 20 | 384.6 | 5.2 | 2.7 (0.8-9.0) | 2.7 (0.8-9.2) | |
| Female | 152 (31.5) | 11 | 247.7 | 4.4 | 2.3 (0.6-8.2) | 2.0 (0.5-7.7) | |
| Age group | |||||||
| ≥35 | 293 (60.8) | 11 | 504.0 | 2.2 | 1.0 | 0.001 | 1.0 |
| 25-34 | 166 (34.4) | 17 | 255.0 | 6.7 | 3.1 (1.4-6.5) | 2.3 (1.1-5.0) | |
| 18-24 | 23 (4.8) | 6 | 27.6 | 21.7 | 10.0 (3.7-26.9) | 6.2 (2.2-17.3) | |
| Education | |||||||
| ≥Secondary | 94 (19.5) | 6 | 151.4 | 4.0 | 1.0 | 0.93 | |
| Primary | 338 (70.1) | 25 | 555.2 | 4.5 | 1.1 (0.5-2.8) | ||
| None | 50 (10.4) | 3 | 80.1 | 3.7 | 0.9 (0.2-3.8) | ||
| Religion | |||||||
| Non Muslim | 383 (79.5) | 30 | 622.6 | 4.8 | 1.0 | 0.16 | |
| Muslim | 99 (20.5) | 4 | 164.0 | 2.4 | 0.5 (0.2-1.4) | ||
| Marital Status | |||||||
| Married | 396 (82.2) | 25 | 646.5 | 3.9 | 1.0 | 0.21 | |
| Steady partner | 86 (17.8) | 9 | 140.1 | 6.4 | 1.7 (0.8-3.6) | ||
| Alcohol use | |||||||
| No | 162 (33.6) | 5 | 265.6 | 1.9 | 1.0 | 0.01 | |
| Yes | 320 (66.4) | 29 | 521.1 | 5.6 | 3.0 (1.1-7.6) | ||
| Extramarital sex | |||||||
| No | 270 (56.0) | 19 | 445.2 | 4.3 | 1.0 | ||
| Yes | 212 (44.0) | 15 | 341.5 | 4.4 | 1.03 (0.5-2.0) | 0.93 | |
| Condom use frequency | |||||||
| Sometimes | 454 (94.2) | 34 | 735.8 | 4.6 | - | - | |
| Always | 28 (5.8) | 0 | 50.9 | 0.0 | - | - | |
| Reported genital ulcer | |||||||
| No | 305 (63.3) | 17 | 502.4 | 3.4 | 1.0 | 0.10 | |
| Yes | 177 (36.7) | 17 | 284.2 | 6.0 | 1.8 (0.9-3.5) | ||
| Reported genital discharge | |||||||
| No | 323 (67.0) | 16 | 531.9 | 3.0 | 1.0 | 0.01 | 1.0 |
| Yes | 159 (33.0) | 18 | 254.7 | 7.1 | 2.3 (1.2-4.6) | 2.5 (1.1-5.5) | |
| Serological syphilis | |||||||
| Negative | 438 (90.9) | 27 | 717.0 | 3.8 | 1.0 | 0.04 | 1.0 |
| Positive | 44 (9.1) | 7 | 69.6 | 10.1 | 2.7 (1.2-6.1) | 3.2 (1.3-7.7) | |
| Receipt of ART by HIV-infected partner | |||||||
| Yes | 152 (31.5) | 3 | 270.6 | 1.1 | 1.0 | 0.002 | 1.0 |
| No | 287 (59.5) | 29 | 480.9 | 6.0 | 5.4 (1.7-17.9) | 4.8 (1.4-16.0) | |
| Data not collected | 43 (8.9) | 2 | 35.1 | 5.7 | 5.1 (0.9-30.7) | 3.9 (0.6-23.8) |
PYO, person-years of observation; RR, unadjusted rate ratio; aRR, adjusted rate ratio (All factors were adjusted gender, age group at study exit, male circumcision, reported genital discharge, serological syphilis and ART use in the HIV-infected partner); CI, confidence interval; LRT, likelihood ratio test.