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. 2011 Aug 31;6(8):e23770. doi: 10.1371/journal.pone.0023770

Table 2. Results of the exercise performance in the population in study.

	CRF patients^#(n = 40)			Controls^#(n = 35)			Controls in room air(n = 35)
	No-Aid	Aid	p	No-Aid	Aid	p	No-Aid	Aid	p
Distance walked at 6MWT, meters	295.2 (90.8)	318.7 (90.0)	0.003	506.2 (50.5)	482.1 (43.6)	<0.001	501.0 (54.4)	484.2 (43.5)	0.002
Distance walked at 6MWT, % predicted	61.4 (17.8)	67.5 (19.0)	0.003	110.9 (14.1)	103.9 (13.8)	<0.001	109.1 (14.9)	105.2 (13.4)	<0.001
Peak effort dyspnoea, Borg^†	4.67 (2.0)	3.81(1.8)	<0.001	1.28 (0.7)	1.51 (0.7)	0.053	1.14 (0.7)	1.48 (0.7)	0.005
Peak leg effort fatigue, Borg^†	3.60 (1.8)	2.65 (1.2)	<0.001	1.40 (0.7)	1.59 (0.7)	0.076	1.31 (0.9)	1.53 (0.7)	0.024
RR at peak effort, breaths/min	22.8 (4.1)	21.6 (3.2)	<0.001	18.7 (1.7)	19.1 (2.0)	0.051	18.7 (2.3)	19.4 (2.2)	0.001
HR max, beats/min	109.2 (9.9)	106.1 (11.5)	0.067	105.4 (9.2)	105.0 (11.4)	0.751	106.5 (10.2)	110.6 (10.7)	0.036
SaO₂ pre-test, %	94.1 (2.3)	94.8 (1.8)	0.601	97.4 (1.0)	97.6 (0.8)	0.905	95.6 (1.3)	95.7 (1.3)	0.231
SaO₂, %	88.7 (3.3)	89.4 (3.8)	0.060	95.5 (1.1)	95.4 (0.9)	0.497	94.0 (1.1)	93.5 (1.2)	0.001
Reduction of SaO₂ during 6MWT, %	5.35 (2.8)	5.36 (3.6)	0.990	1.86 (1.1)	2.24 (1.0)	0.049	1.62 (1.0)	2.20 (1.2)	<0.001
Nadir of SaO₂ during 6MWT, %	84.1 (5.9)	85.5 (5.8)	0.019	93.7 (1.5)	93.7 (1.8)	0.926	91.4 (1.9)	91.6 (1.8)	0.546

Value expressed as mean ± SD.

^#

Test performed breathing oxygen at 3 L/min.

^†

Differences calculated using no-parametric test of Kruskal-Wallis and Wilcoxon test.