Figure 8. Model.

Panel A underscores the fact that the dimers of the αA-crystalline particles (yellow) skip a position in the filament and become spaced at twice the distance (∼14 nm instead of ∼7 nm). At the right side, a kinked file of “real” yellow conjugates reflects this condition. Panel B shows two neighboring filaments decorated with monomers of αA-crystalline. In addition of being spaced at ∼7 nm apart, the αA-crystalline monomers occupy the vertices of isosceles triangles. At the right side, distributions of “real” blue conjugates reflect this condition. Panel C shows how the association of three filaments decorated with monomers at the minimum distance form tetrahedrons or pyramids. At the right side, blue and the yellow conjugates reflect this condition. Panel D shows a larger tetrahedron (the “bead”) formed by the assembly of smaller αA-crystalline particles. At the right side, a “real” particle reflects this condition. Panel E shows a region where these “beads” associate to form the larger “aggregates.” The right side panel shows a view of this type of “aggregate” where the “beads” adopt cobblestone patterns in the interior.