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. 2011 Aug 31;6(8):e23631. doi: 10.1371/journal.pone.0023631

Table 3. Demographics and distribution of parameters that are known to affect graft and patient survival after kidney transplantation.

Demographics Absence of HLA-C2(n = 303) Presence of HLA-C2(n = 457) P value
Recipient age 43.0 (CI 41.2–44.8) 42.3 (CI 40.9–43.6) 0.49*
Donor age 43.5 (CI 41.6–45.4) 43.5 (CI 42.1–44.9) 0.96*
Recipient sex M∶F 191∶112 278∶179 0.55+
Donor sex M∶F 180∶123 236∶221 0.03+
Seropositive CMV in recipient 169 240 0.43+
Seropositive CMV in donor 150 212 0.41+
Type of transplant; Deceased donor: Live donor 258∶45 382∶75 0.60+
Number of transplant
1 256 398 0.26+
2 39 47
3 8 12
Acute Rejection 86 129 0.96+
Type of CNI; Cyclosporin: Tacrolimus 290∶15 434∶21 0.90+
Anti-CD25 monoclonal antibody 50 82 0.59+
HLA mismatch (no. of antigens)
0 44 58 0.62+
1 31 41
2 128 206
3 71 108
4 15 25
5 10 14
6 4 5
Mean mismatches per patient 2.09 2.15
DR locus mismatch (no. of antigens)
0 207 297 0.42+
1 83 142
2 13 18
Mean mismatches per patient 0.36 0.41

As the analysis involved the comparison between absence of HLA-C2 in the recipient versus presence of HLA-C2 in the recipient groups were divided accordingly. Absence of HLA-C2 represents HLA-C1 homozygous whereas presence of HLA-C2 combines both heterozygous and HLA-C2 homozygous groups. CI is 95% confidence interval.

*indicates significance by ANOVA test,

+

indicates significance by Kendall's tau-b test.