Table 4. Cox regression multivariable analysis for all factors that may influence outcomes after kidney transplantation.
| Significance | Hazard ratio | 95% CI | Significance | Hazard ratio | 95% CI | Significance | Hazard ratio | 95% CI | |
| Graft survival, death non-censored | Graft survival, death censored | Patient survival | |||||||
| Recipient age | 0.29 | 0.99 | 0.98–1.01 | 0.002 | 0.98 | 0.96–0.99 | 0.001 | 1.05 | 1.02–1.08 |
| Donor age | 0.04 | 1.01 | 1.00–1.03 | 0.02 | 1.02 | 1.00–1.03 | 0.69 | 1.01 | 0.98–1.03 |
| Recipient sex | 0.77 | 1.05 | 0.75–1.47 | 0.50 | 1.20 | 0.71–2.05 | 0.88 | 0.95 | 0.49–1.85 |
| Donor sex | 0.61 | 1.09 | 0.79–1.51 | 0.52 | 1.14 | 0.77–1.67 | 0.19 | 0.63 | 0.32–1.25 |
| Seropositive CMV in recipient | 0.18 | 0.78 | 0.55–1.12 | 0.19 | 0.76 | 0.51–1.15 | 0.71 | 0.87 | 0.41–1.84 |
| Seropositive CMV in donor | 0.48 | 0.89 | 0.63–1.24 | 0.41 | 0.85 | 0.57–1.25 | 0.84 | 0.93 | 0.46–1.87 |
| Type of transplant: Deceased versus Live | 0.02 | 2.96 | 1.18–7.44 | 0.11 | 2.17 | 0.85–5.54 | 0.77 | 1.05 | 0.76–1.48 |
| Number of transplant | |||||||||
| Comparisons made to 1st transplant | |||||||||
| 2 | 0.83 | 0.94 | 0.55–1.62 | 0.17 | 0.61 | 0.30–1.24 | 0.11 | 2.10 | 0.86–5.14 |
| 3 | 0.49 | 1.52 | 0.46–5.03 | 0.34 | 1.80 | 0.54–6.08 | 0.99 | 0.00 | 0.00 |
| Acute Rejection | 0.35 | 1.17 | 0.84–1.65 | 0.15 | 1.33 | 0.91–1.95 | 0.38 | 0.70 | 0.32–1.55 |
| Cyclosporin versus Tacrolimus | 0.35 | 0.64 | 0.25–1.65 | 0.57 | 1.53 | 0.35–6.63 | 0.003 | 0.15 | 0.04–0.51 |
| Anti-CD25 monoclonal antibody | 0.62 | 1.15 | 0.66–1.98 | 0.89 | 1.04 | 0.58–1.89 | 0.36 | 2.03 | 0.45–9.13 |
| HLA mismatch (no. of antigens) | |||||||||
| Comparisons made to 0 HLA mismatch | |||||||||
| 1 | 0.07 | 1.90 | 0.96–3.75 | 0.05 | 2.13 | 0.99–4.61 | 0.76 | 1.28 | 0.27–5.96 |
| 2 | 0.29 | 1.37 | 0.77–2.45 | 0.40 | 1.34 | 0.68–2.63 | 0.70 | 1.25 | 0.40–3.87 |
| 3 | 0.86 | 0.94 | 0.46–1.94 | 0.61 | 0.80 | 0.33–1.90 | 0.83 | 1.16 | 0.31–4.36 |
| 4 | 0.04 | 2.46 | 1.05–5.75 | 0.05 | 2.60 | 1.00–6.75 | 0.78 | 1.40 | 0.14–14.28 |
| 5 | 0.63 | 1.56 | 0.25–9.66 | 0.28 | 2.69 | 0.45–16.03 | 0.98 | 0.00 | 0.00 |
| 6 | 0.43 | 3.01 | 0.20–45.16 | 0.23 | 6.67 | 0.30–149.09 | 0.99 | 0.00 | 0.00 |
| DR locus mismatch (no. of antigens) | |||||||||
| Comparisons made to 0 DR mismatch | |||||||||
| 1 | 0.56 | 1.15 | 0.73–1.80 | 0.47 | 1.22 | 0.71–2.08 | 0.99 | 1.01 | 0.42–2.38 |
| 2 | 0.50 | 0.55 | 0.09–3.17 | 0.25 | 0.26 | 0.03–2.55 | 0.18 | 8.53 | 0.39–188.23 |
| HLA-C2 absent in recipient | 0.007 | 1.55 | 1.13–2.13 | 0.02 | 1.53 | 1.06–2.21 | 0.19 | 1.54 | 0.80–2.94 |
| HLA-Bw4 absent in recipient | 0.35 | 1.17 | 0.84–1.65 | 0.50 | 1.20 | 0.71–2.05 | 0.88 | 0.95 | 0.49–1.85 |
Statistically significant associations are indicated in bold.