Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Two possible mechanisms by which an RNA destabilizing element could accelerate ribonuclease cleavage. (A) The catalytic active site of the ribonuclease (scissors) binds directly to the RNA destabilizing element (stem–loop) and cleaves it. (B) An RNA-binding domain of the ribonuclease or an associated protein binds to the RNA destabilizing element, thereby facilitating access of the ribonuclease active site to a cleavage site elsewhere in the RNA.
