Table S1.
Gene sets tested in gene set enrichment analysis
| Gene set ID number | Description | Number of genes | Reference |
|---|---|---|---|
| 1 | Beta oxidation of fatty acids | 46 | KEGG |
| 2 | Fatty acid beta oxidation | 24 | GO |
| 3 | Genes linked to PFOS and PFOA exposure in chickens | 36 | [1] |
| 4 | Gap junction intracellular communication | 96 | KEGG |
| 5 | Genes linked to oxidative stress in hepatocytes from freshwater tilapia after PFOS and PFOA exposure | 17 | [2] |
| 6 | Oxidative stress | 94 | GO |
| 7 | Regulation of fatty acid oxidation | 18 | GO |
| 8 | Steroid metabolism | 11 | KEGG |
| 9 | Cholesterol biosynthesis | 9 | KEGG |
| 10 | Cholesterol metabolism | 44 | GO |
| 11 | Steroid biosynthesis | 17 | KEGG |
| 12 | Cholesterol biosynthesis | 9 | GO |
| 13 | Genes linked to PFOS exposure in rat | 19 | [3] |
| 14 | Genes linked to PFOS and PFOA exposure in rat | 13 | [3] |
| 15 | Xenobiotic metabolic process | 13 | GO |
| 16 | Xenobiotic metabolism | 70 | KEGG |
| 17 | Synthesis and degradation of ketone bodies | 9 | KEGG |
| 18 | Fatty acid elongation | 10 | KEGG |
| 19 | Fatty acid metabolic process | 134 | GO |
| 20 | Unsaturated fatty acid biosynthesis | 22 | KEGG |
| 21 | Fatty acid biosynthesis | 7 | KEGG |
| 22 | Fatty acid biosynthesis and regulation | 19 | GO |
| 23 | Apoptosis | 88 | KEGG |
| 24 | Genes linked to PFOS exposure in zebrafish | 6 | [4] |
| 25 | Bile acid biosynthesis | 16 | KEGG |
| 26 | Bile acid metabolic process | 11 | GO |
| 27 | Genes linked to PFOS exposure in rat liver | 24 | [5] |
| 28 | Genes linked to PFOS exposure in hepatocytes from Atlantic salmon | 27 | [6] |
| 29 | Genes linked to PFOS exposure in carp | 20 | [7] |
| 30 | Genes linked to PFOS exposure in chicken embryo hepatocytes | 6 | [8] |
| 31 | Genes linked to PFOS exposure in bottlenose dolphin | 8 | [9] |
| 32 | Genes linked to PFOS exposure in rats | 4 | [10] |
| 33 | Genes linked to PFOS exposure in mouse | 8 | [11] |
| 34 | Glycolysis | 63 | KEGG |
| 35 | Glucose metabolic process | 57 | GO |
| 36 | Diabetes 2 | 44 | KEGG |
| 37 | Genes linked to PFOA exposure in rat | 76 | [3] |
| 38 | Leukocyte transendothelial migration | 116 | KEGG |
| 39 | Citric cycle | 32 | KEGG |
| 40 | Genes linked to PFOA exposure in mouse liver | 4 | [12] |
| 41 | Retinol metabolism | 64 | KEGG |
| 42 | PPAR | 69 | KEGG |
| 43 | Insulin signaling | 138 | KEGG |
| 44 | Glucose homeostasis | 22 | GO |
| 45 | Retinol metabolic process | 7 | GO |
| 46 | Citric acid cycle | 7 | GO |
| 47 | Insulin receptor signaling pathway | 33 | GO |
| 48 | Lipid transport | 95 | GO |