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. Author manuscript; available in PMC: 2012 Feb 19.
Published in final edited form as: Cell. 2011 Aug 19;146(4):621–632. doi: 10.1016/j.cell.2011.06.048

Figure 2. Crystal structures of type I IFN receptor components and ligand-receptor complexes.

Figure 2

Ribbon representations and designated resolutions of (A) IFNAR1ΔSD4. (B) IFNAR2-D2. (C) The IFNα2(HEQ)-IFNAR2 binary complex (IFNα2(HEQ) brown, IFNAR2 green). (D) Ternary complex of IFNAR1 (blue), IFNAR2 (green) and IFNα2(YNS). (E) Ternary complex of IFNAR1 (blue), IFNAR2 (green) and IFNω. The membrane-proximal SD4 domain of IFNAR1 is depicted as an oval. See also Table S1 and Figure S2.