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. Author manuscript; available in PMC: 2011 Sep 2.
Published in final edited form as: J Membr Biol. 2011 Jan 12;239(1-2):27–34. doi: 10.1007/s00232-011-9343-0

Table 1.

Overview of experimental conditions for vesicle leakage, microbial sterilization, and hemolysis. The vesicle leakage experiments are performed at much lower peptide-to-lipid ratios than the biological assays, impeding direct comparisons.

Large Unilamellar Vesicle Bacteria
Diameter= 0.1 μm Diameter= 1.0 μm
Vesicles/ml = 2×1012 Cells/ml = 1×105
Lipids/vesicle = 1×105 Lipids/cell = 2×107
Lipid conc. = 5×10−4 M Lipid conc. = 2×10−9 M
Peptide conc. = 5×10−6 M Peptide conc. = 5×10−6 M
Peptide/Lipid= 0.01 Peptide/Lipid= 1000

Fungus Cell Red Blood Cell
Diameter= 5 μm Diameter= 10 μm
Cells/ml = 1×105 Cells/ml = 1×108
Lipids/cell = 1×108 Lipids/cell = 1×109
Lipid conc. = 2×10−8 M Lipid conc. = 1×10−5 M
Peptide conc. = 5×10−6 M Peptide conc. = 5×10−6 M
Peptide/Lipid= 200 Peptide/Lipid= 0.5