Figure 4.

 Rpd3 mutants are partially defective for repression function when artificially recruited to a heterologous promoter. β-Galactosidase activities of rpd3 deletion strains expressing the indicated Rpd3 derivatives fused to the LexA DNA-binding domain. (−) The LexA only control. Fold repression represents the ratio of β-galactosidase activities in strains containing plasmids that either lack (shaded bars) or contain (open bars) four LexA operators upstream of the CYC1 promoter. Values are normalized to A₆₀₀ and represent the average of at least seven independent transformants; they are accurate to ±10%.