Table 2. Enriched functional terms for genes with synchronous expression commonly occurring in mouse anti-aging processes treated by dietary restriction (EOD) and resveratrol intervention (SDLR, SDHR).
Term(Database category) | EOD | SDLR | SDHR |
ES(count) | ES(count) | ES(count) | |
Acetylation(SP) | 0.00012(26) | <0.0001(31) | 0.00012(44) |
Phosphoprotein (Phosphorylation)(SP) | <0.0001(55) | 0.037(47) | NA |
Ubl conjugation (Ubiquitinylation)(SP) | 0.046(7) | 0.085(7) | NA |
Hydrolase(SP) | 0.068(13) | 0.095(14) | NA |
Circadian rhythm(KEGG) | 0.082(2) | NA | 0.012(3) |
Generation of precursor metabolites and energy(GO_BP) | NA | 0.060(5) | 0.018(8) |
Cellular amino acid derivative metabolic process(GO_BP) | 0.040(4) | NA | 0.057(5) |
Phospholipid metabolic process(GO_BP) | NA | 0.065(4) | 0.087(5) |
Energy derivation by oxidation of organic compounds(GO_BP) | 0.015(4) | NA | 0.080(4) |
Glycerolipid biosynthetic process(GO_BP) | NA | 0.042(3) | 0.021(4) |
Lipid metabolism(SP) | NA | 0.0082(5) | 0.014(6) |
Protein localization/transport(GO_BP) | 0.048(9) | 0.026(10) | 0.088(13) |
Transport(SP) | NA | 0.0091(18) | 0.098(23) |
Transit peptide(SP) | NA | 0.0013(10) | <0.0001(16) |
Prion Pathway(BIOCARTA) | 0.090(2) | 0.098(2) | 0.011(4)(KEGG) |
Mitochondrion(SP) | NA | <0.0001(17) | <0.0001(22) |
Cytoplasm(SP) | 0.00056(29) | 0.0070(29) | 0.066(41) |
Endosome(SP) | 0.017(5) | 0.028(5) | 0.057(6) |
Lysosome(SP) | NA | 0.051(4) | 0.00081(8) |
Note: refer to table 1.