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. 2011 Sep 2;6(9):e24134. doi: 10.1371/journal.pone.0024134

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Martens et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Panels A and B respectively show abundant expression of PPP1R1A protein in insulin+ cells and absence in glucagon+ cells in islets from 10 w old rats. Beta cell-selective expression of PTPRN and HADH proteins in human beta cells is illustrated in panels C and D respectively. All images are representative of at least 3 different organs with at least 3 sections analyzed per pancreas.