Figure 4.

Crystallin gene-expression study of wild-type and mutant lens. RT–PCR analysis of hprt, αA-, αB-, βA3/A1-, γA-, γB-, γC-, γD-, γE-, and γF-crystallins at 12.5 and 15.5 dpc. αB-Crystallin expression in the Sox1 mutant eye at 15.5 dpc is up-regulated possibly due to hypertonic stress (Dasgupta et al. 1992).