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. 1998 Mar 15;12(6):868–879. doi: 10.1101/gad.12.6.868

Figure 3.

Figure 3

 Schematic representation of ICP27 coding region showing the putative NES. The 512-amino-acid coding region of ICP27 is represented. The putative NES from residues 5–17 is shown as are the two arginine-rich regions, R1 (residues 141–151) and R2 (162–171) that follow the NLS (residues 110–137) (Hibbard and Sandri-Goldin 1995; Mears et al. 1995). The activation region extends from residues 260–512 (Hardwicke et al. 1989) and the splicing repressor region, which includes a cysteine–histidine–zinc-finger-like domain (CCHC) encompasses residues 406–512 (Sandri-Goldin and Hibbard 1996).