Table 3.
Patient | EORTC/MSG response | Time to GMI normalization, days | No. of GMI tests with negative resultsa | Lung infiltrates | Concomitant conditions | Survival after IA diagnosis | Survival after negative GMI test result |
1 | Failure, stable response | 57 | 2 | Stable | None | Alive | 3 years |
2 | Failure, death | 12 | 3 | Worse | No IA at autopsy | 15 days | 3 days |
3 | Failure, death | 20 | 18 | Worse | PE, CMV disease | 37 days | 17 days |
4 | Failure, death | 7 | 36 | New infiltrates | Pseudomonas aeruginosa pneumonia and bacteremia | 42 days | 35 days |
5 | Failure, death | 4 | 18 | Worse | CMV colitis, VRE sepsis, cardiogenic shock | 22 days | 15 days |
6 | Failure, death | 17 | 15 | Not tested | P. aeruginosa pneumonia, VRE sepsis | 33 days | 16 days |
7 | Failure, death | 9 | 30 | Improved | PJP, CMV colitis | 39 days | 30 days |
8 | Failure, death | 13 | 20 | Worse | Klebsiella pneumoniae pneumonia | 32 days | 19 days |
9 | Failure, death | 5 | 26 | Worse | Accidental extubation, VRE sepsis | 31 days | 26 days |
10 | Failure, death | 4 | 15 | Not tested | Disseminated adenoviral infection, Clostridium difficile colitis,VRE sepsis | 19 days | 15 days |
Abbreviations: CMV, cytomegalovirus; PE, pulmonary embolism; PJP, Pneumocystis jirovecii pneumonia; VRE, vancomycin-resistant enterococci.
Number of tests between first negative test result and death or last follow-up.