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. 2011 Oct 1;53(7):671–676. doi: 10.1093/cid/cir441

Table 3.

Characteristics of the 10 Patients With Invasive Pulmonary Aspergillosis (IA) Who Had a Discordant Response (Failure According to European Organization for Research and Treatment of Cancer/Mycosis Study Group [EORTC/MSG] Definition, Success According to Aspergillus-Specific Galactomannan Index [GMI] Definition)

Patient EORTC/MSG response Time to GMI normalization, days No. of GMI tests with negative resultsa Lung infiltrates Concomitant conditions Survival after IA diagnosis Survival after negative GMI test result
1 Failure, stable response 57 2 Stable None Alive 3 years
2 Failure, death 12 3 Worse No IA at autopsy 15 days 3 days
3 Failure, death 20 18 Worse PE, CMV disease 37 days 17 days
4 Failure, death 7 36 New infiltrates Pseudomonas aeruginosa pneumonia and bacteremia 42 days 35 days
5 Failure, death 4 18 Worse CMV colitis, VRE sepsis, cardiogenic shock 22 days 15 days
6 Failure, death 17 15 Not tested P. aeruginosa pneumonia, VRE sepsis 33 days 16 days
7 Failure, death 9 30 Improved PJP, CMV colitis 39 days 30 days
8 Failure, death 13 20 Worse Klebsiella pneumoniae pneumonia 32 days 19 days
9 Failure, death 5 26 Worse Accidental extubation, VRE sepsis 31 days 26 days
10 Failure, death 4 15 Not tested Disseminated adenoviral infection, Clostridium difficile colitis,VRE sepsis 19 days 15 days

 Abbreviations: CMV, cytomegalovirus; PE, pulmonary embolism; PJP, Pneumocystis jirovecii pneumonia; VRE, vancomycin-resistant enterococci.

a

Number of tests between first negative test result and death or last follow-up.