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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Exp Biol Med (Maywood). 2011 Jul 12;236(9):1051–1063. doi: 10.1258/ebm.2011.010400

Figure 6. siRNA knockdown of AMPKα causes significant decreases in protein expression of POXO3α, Mn SOD, thioredoxin, but increases in PERK in high glucose challenged ARPE-19 cells.

Figure 6

AMPKα was knocked down by its specific siRNA in the zeaxanthin (1.25 μM) treated ARPE-19 cells under a high glucose challenge. Alteration of protein expression was monitored by Western blot. Representative images were shown (A). β-actin was used as an equal loading control to normalize each protein expression. Relative band intensity of each protein to β-actin was used for graphing and statistic analysis (B). * p<0.05 vs. the Vehicle groups