Skip to main content
. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Nature. 2011 Aug 14;477(7362):107–110. doi: 10.1038/nature10324

Figure 3.

Figure 3

A: CD-spectra of native tetrameric αSyn (isolated under non-denaturing conditions from human RBC) before vs. after addition of PC/PS SUV (protein/lipid 1:500). B: CD spectra of recombinant αSyn monomer purified from E. coli alone and with addition of PC/PS SUV (protein/lipid 1:500). C: SPR sensorgram of equal protein concentrations of αSyn recombinant monomer vs. endogenous tetramer injected on a L1 chip covered with a PC/PS membrane. D: Amyloid-type aggregation kinetics of recombinant αSyn monomer vs. native RBC tetramer monitored by ThT fluorescence; average values from 3 independent experiments (error bars = SD; some SD for RBC-derived αSyn are smaller than the symbol size). AU, arbitrary units.