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Effect of depolarization on the distribution of SynGAP and PSD-95. Immunogold label for SynGAP Ab1 (A, B), SynGAP Ab2 (C, D), and PSD-95 (E, F) under basal conditions (left column) and after two minutes of treatment with high K+ (right column). Upon depolarization, the distribution of label for SynGAP moves away from the PSD core and into the contiguous network, while label for PSD-95 remains unchanged. Scale bar = 100 nm.
