MS/MS fragmentation spectra of several novel neuropeptides in C. sapidus SG by ESI-Q-TOF: (a) orcokinin (DFDEIDRSGFGFA m/z 1475.64), all y-ions and b-ions are detected; (b) Ork/Orcomyotropin-related peptide (TPRDIANLY m/z 1062.56), almost all b-ions from b2 to b8 are detected and are very abundant compared to the incomplete y-ion series; (c) orcomyotropin (FPAFTTGFGSH m/z 1168.54), y1-y8, b1-b8 except b7 are detected with the most abundant fragment ions being a3 and a4; (d) PDH-related peptide (pQELHVPEREA m/z 1190.57), y1-y8,b2-b4 and b8 are detected.