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. Author manuscript; available in PMC: 2012 Sep 15.
Published in final edited form as: Neuroscience. 2011 Jun 2;191:148–158. doi: 10.1016/j.neuroscience.2011.05.045

Figure 2. DR performance in young and aged OVX Rhesus monkeys with and without E replacement.

Figure 2

Young OVX animals perform the DR task with equivalent average accuracy whether treated with cyclical estrogen therapy or with vehicle alone. Aged OVX monkeys perform significantly less accurately than young animals (p < 0.03 at all time points), but this deficit is reversed by cyclical estrogen treatment. (E = estrogen-treated, other animals are treated with vehicle alone; reproduced from Hao et al., 2007)