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. Author manuscript; available in PMC: 2012 Sep 16.
Published in final edited form as: Adv Drug Deliv Rev. 2011 Jul 8;63(12):1042–1050. doi: 10.1016/j.addr.2011.06.012

Table 1.

Examples of surface modification procedures, effects on the hemocompatibility, and examples of biomedical devices with each surface modification.

PEG 1 Low Low Varying Low Experimental (Drug delivery systems 2) [49–53]
Low energy plasma Varying - 3 Low - Experimental [46, 66, 67]
Heparin Low Low Moderate Low Perfusion systems (e.g oxygenators), central venous catheters, stents [68–73]
RCA 4 - - Low - Stents [52, 74]
Anti-RCA peptide - - Low - Experimental [85, 87]
Molecular imprint - - Low - Drug eluting contact lenses [92, 94]
Nanostructure - - Low Low Dental titanium implants [98, 105]
1

Polyethylene glycol;

2

Discussed in chapter 6 in this issue of Advanced Drug Delivery Reviews;

3

Little or no data regarding systematic investigation of these parameters is available;

4

Regulators of complement activation