Table 2.
Proportion of total serotypes in 6 Asian countries (A) | Serotype-specific efficacy of RV512 (B) | Attributable effectiveness: Base case scenario† (%) | Attributable effectiveness: Sensitivity analysis§ (%) | |
G1 | 0.32 | 0.95 | 30 | 30 |
G2 | 0.14 | 0.88 | 12 | 12 |
G3 | 0.22 | 0.93 | 20 | 20 |
G4 | 0.04 | 0.89 | 4 | 4 |
G9 | 0.14 | 1.0 | 14 | 14 |
G12 | 0.02 | 1.0 | 2 | 2 |
M/O/U†,§ | 0.13 | - | 7 | 0 |
Overall weighted effectiveness in the region | 89 | 82 |
Base case scenario: assumes 50% efficacy against mixed and nontypeable serotypes.
Sensitivity analysis: assumes 0% efficacy against mixed and nontypeable serotypes. M/O/U, mixed, other, untypeable; RGE, otavirus gastroenteritis; RV5, oral pentavalent rotavirus vaccine.