Table 1.
| Low AW group | Higher AW group | ||||
|---|---|---|---|---|---|
| PLA | FMZ/GBP | PLA | FMZ/GBP | Test for difference | |
| N | 18 | 26 | 9 | 7 | |
| Age | 47.2 ± 11.2 | 44.1 ± 11.9 | 50.3 ± 8.5 | 46.7 ± 5.6 | Not significant |
| Gender N | |||||
| -Male | 14 | 20 | 6 | 6 | Not significant |
| -Female | 4 | 6 | 3 | 1 | Not significant |
| Education (years) | 14.9 ± 2.6 | 14.4 ± 2.2 | 15.0 ± 1.9 | 13.4 ± 2.5 | Not significant |
| Baseline drinking | |||||
| -Heavy drinking days, % | 91.1 ± 10.0 | 84.3 ± 16.0 | 90.2 ± 16.0 | 86.2 ± 22.0 | Not significant |
| -Days abstinent, % | 5.5 ± 5.9 | 6.4 ± 8.9 | 9.1 ± 16.0 | 12.9 ± 22.0 | Not significant |
|
Alcohol Dependence Scale (range: 0–47) |
12.4 ± 7.0 | 12.6 ± 5.8 | 21.2 ± 10.6 | 17.6 ± 6.9 | Higher AW > Low |
| Years of alcohol dependence | 11.1 ± 8.9 | 10.3 ± 8.4 | 16.3 ± 13.6 | 7.5 ± 8.4 | Not significant |
|
Past other substance dependence N |
1 | 8 | 2 | 2 | Low AW/FMZ-GBP > Low AW/PLA |
|
POMS Depression subscale (range: 0–20) |
6.3 ± 5.6 | 5.7 ± 5.0 | 10.0 ± 6.7 | 5.3 ± 5.0 | Not significant |
Demographic and baseline variables, by medication group within alcohol withdrawal (AW) group. All figures except Ns are means ± standard deviations.
FMZ/GBP = flumazenil/gabapentin; PLA = placebos; POMS = Profile of Mood States.