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. Author manuscript; available in PMC: 2011 Sep 4.
Published in final edited form as: Peptides. 2009 Nov 26;31(2):357–369. doi: 10.1016/j.peptides.2009.11.019

Table 2.

Effects of three common surgical procedures compared to a dietary approach on body mass index (BMI) and circulating ghrelin levels.

Intervention/Technique Duration Effects on BMI Effects on circulating ghrelin Reference
Roux-en-Y gastric bypass 9 – 31 months 36% reduction of BMI 77% reduction of the 24 h ghrelin profile (area under the curve) [37]
Sleeve gastrectomy 12 months 36% reduction of BMI 34% reduction of fasting total ghrelin plasma levels [76]
Gastric banding 18 months 38% reduction of BMI 65% increase of fasting total ghrelin plasma levels [87]
Diet 6 months 9% reduction of BMI 110% increase of fasting total ghrelin plasma levels [87]