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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Hum Genet. 2011 Apr 26;129(6):585–595. doi: 10.1007/s00439-011-0993-x

Figure 1.

Figure 1

Three main approaches to DNA methylation microarray analysis. A) Black circles denote methylated CpGs and white circles denote unmethylated CpGs. B) Illumina’s bisulfite treatmentbased approach. Cy3/Cy5 labeling varies between Infinium I and Infinium II probes, C) Affinity enrichment using methylcytosine immunoprecipitation (IP) D) Methylation-sensitive restriction digestion using McrBC.