Table 3.

Sensitivity and specificity for CRP, IL-8, and PCT at presentation of febrile neutropenia (t = 0) and after 24–48 h (t = 24–48) to distinguish bacterial infection from other causes of fever

	AUC (95% CI)	Cut-off	Sensitivity (t = 0)	Specificity (t = 0)	Sensitivity (t = 24–48)	Specificity (t = 24–48)
CRP	0.609 (0.392–0.826)	40 mg/l	69%	62%	100%	42%
IL-8	0.807 (0.644–0.970)	60 ng/l	92%	54%	100%	57%
PCT	0.840 (0.710–0.970)	0.25 ng/ml	79%	77%	100%	53%

AUC area under the curve; CI confidence interval