Figure 6.

 Expression of Bmp2 and Bmp7 is reduced in limbs of Jag2^ΔDSL homozygotes. (A,B) Bmp2 expression. Bmp2 expression is reduced in Jag2^ΔDSL homozygous mutants between the developing digits 2 and 3 (white arrow). (C,D) Bmp7 expression. Bmp7 expression is reduced in distal regions of the interdigital mesenchyme in the Jag2^ΔDSL mutants. (E,F) Bmp4 expression. Bmp4 expression in distal mesenchyme is unaffected in the Jag2^ΔDSL mutants. Note the altered morphology of the foot plate in the Jag2^ΔDSL homozygous mutants (B,D,F). All embryos shown are at E13.5.