Figure 4.

Functional importance of GABA in the ventral pallidum (VP). (A) Intraoral infusion of saccharin solution after CTA acquisition increased GABA release in the VP. (B) The intake of saccharin in the vehicle-injected control group (V) was very small after CTA acquisition, but it increased significantly after microinjection of bicuculline [50 ng (B)]. (C) Muscimol (100 ng) injected into the VP suppressed the intake of saccharin which was significantly different from the intake after vehicle injection at each time point. (D) Mean ± SEM number of ingestive and aversive taste reactivity responses to intraoral infusion of 5 mM saccharin after microinjection of muscimol or vehicle in the VP. *p < 0.05. (Modified from Shimura et al., 2006; Inui et al., 2007, 2009.)