Table 3.
Chronic conditions | NSAID use % (n = 357) | NSAID use (n = 176) | Cox-2 inhibitor use (n = 187) | ||||
---|---|---|---|---|---|---|---|
Joint pain | No | 2.2 (23) | < 0.01 | 1.6 (17) | < 0.01 | 0.7 (7) | < 0.01 |
Yes | |||||||
Diagnosed as arthritis | 27.6 (247) | 11.2 (100) | 16.9 (151) | ||||
Not diagnosed as arthritis | 6.7 (79) | 4.9 (57) | 2.0 (23) | ||||
Cardiovascular disease/stroke | No | 10.2 (289) | < 0.01 | 5.3 (150) | 0.05 | 5.1 (144) | < 0.01 |
Yes | 20.0 (60) | 8.0 (24) | 12.0 (36) | ||||
MI/angina | No | 10.6 (308) | < 0.01 | 5.4 (158) | 0.28 | 5.3 (155) | < 0.01 |
Yes | 18.8 (42) | 7.1 (16) | 11.6 (26) | ||||
> 15% 10 year CVD risk | No | 10.4 (214) | 0.01 | 5.6 (115) | 0.44 | 5.0 (103) | < 0.01 |
Yes | 14.7 (56) | 6.6 (25) | 8.4 (32) | ||||
Hypertension* | No | 7.7 (140) | < 0.01 | 4.6 (83) | < 0.01 | 3.2 (59) | < 0.01 |
Yes | 16.0 (217) | 6.9 (93) | 9.5 (128) | ||||
Kidney disease** | No | 9.9 (245) | < 0.01 | 5.4 (134) | 0.58 | 4.7 (116) | < 0.01 |
Yes | 15.9 (109) | 6.0 (41) | 10.1 (69) | ||||
Primary care provider visits in previous year |
None | 3.5 (8) | < 0.01 | 3.1 (7) | < 0.01 | 0.4 (1) | < 0.01 |
1-4 | 6.5 (103) | 3.6 (56) | 3.0 (47) | ||||
≥ 5 | 18.0 (239) | 8.4 (111) | 10.0 (133) | ||||
Medication use | |||||||
Anti-hypertensives | No | 9.3 (211) | < 0.01 | 5.1 (117) | 0.11 | 4.3 (98) | < 0.01 |
Yes | 16.3 (146) | 6.6 (59) | 9.9 (89) | ||||
Diuretics | No | 10.7 (325) | < 0.01 | 5.5 (166) | 0.31 | 5.4 (164) | < 0.01 |
Yes | 24.1 (32) | 7.5 (10) | 17.3 (23) | ||||
ACE inhibitors | No | 11.2 (314) | 0.69 | 5.3 (150) | 0.15 | 6.0 (169) | 0.43 |
Yes | 11.9 (43) | 7.2 (26) | 5.0 (18) | ||||
Gastro-esophageal reflux | No | 9.0 (243) | < 0.01 | 4.9 (134) | < 0.01 | 4.1 (112) | < 0.01 |
Yes | 24.7 (114) | 9.1 (42) | 16.3 (75) |
*Hypertension: systolic ≥ 140 mm Hg and/or diastolic ≥ 90 mm Hg or use of anti-hypertensive medication.
**Kidney disease: GFR < 60 ml/min/1.73 m2, GFR > 60 and proteinuria.