Table 1.
Characteristics of the genotyped subjects from the Ashkenazi Jewish, NINDS, and CIDR/Pankratz et al 2009 datasets
| Ashkenazi Jews | NINDS | CIDR/Pankratz et al 2009 | Overall | |||||
|---|---|---|---|---|---|---|---|---|
| Case | Control | Case | Control | Case | Control | Case | Control | |
| Subjects (%) | 268(60.1) | 178(39.9) | 923(53.6) | 798(46.4) | 859(50.0) | 860(50.0) | 2050(52.8) | 1836(47.2) |
| Mean age at onset/examination Year ± SD* | 59.9 ± 12.1 | 69.8 ± 8.8 | 58.5 ± 13.2 | 58.6 ± 16.4 | 61.8 ± 10.9 | 54.8 ± 13.0 | 60.0 ± 12.2 | 57.9 ± 14.9 |
| Male(%) | 255(57.2) | 886(51.5) | 850(49.4) | 1991(51.2) | ||||
| Proportion of EOPD# | 24.5% | 26.0% | 15.0% | 21.3% | ||||
| Total | 446 | 1721 | 1719 | 3886 | ||||
| Genotyping rate | 99.85 | 99.79 | 99.81 | 99.82 | ||||
| Markers passing QC | 525124 | 517805 | 334161 | |||||
* Age at onset for cases and age at examination for controls, # EOPD: Early Onset of PD, with age at onset younger than or equal to 50