Table 1. Clinical and neuropathological information for NPH cases.
Case ID | Gender | Education | Comorbidity#1 | Comorbidity#2 | Received Shunt? | Age at Death | NP Dx1 | NP Dx2 | NP Dx3 | NP Dx4 |
---|---|---|---|---|---|---|---|---|---|---|
1 | F | 16 | + | 82 | AD | Argyrophilic grains, mesial lobe | ||||
2 | M | 14 | AD | Parkinsonism | + | 80 | AD | Microscopic DLB (sufficient for dx) | Chronic superficial cortical gliosis | |
3 | M | 16 | AD | + | 79 | AD | Cerebral white matter rarefaction | Old cortical microscopic infarct, left middle frontal gyrus | ||
4 | F | 15 | AD | Parkinsonism | + | 82 | AD | Microscopic DLB (insufficient for diagnosis) | Argyrophilic grains, mesial lobe | Glial tauopathy, basal ganglia |
5 | M | 14 | MCI | + | 77 | AD | Cerebral white matter rarefaction | Acute right capsular hemorrhage | Old hemorrhagic microscopic infarct | |
6 | M | 20 | PD | MCI | + | 77 | PSP | Microscopic changes of AD (insufficient for diagnosis) | Mild bilateral chronic subdural hematoma | |
7 | M | Not known | Dementia | Seizure disorder | + | 94 | AD | Chronic inflammatory cell infiltrates | ||
8 | F | Not known | AD | + | 95 | AD | Microscopic DLB (insufficient for diagnosis) | Cerebral white matter rarefaction | Arachnoid cyst, left parietal lobe | |
9 | F | 16 | AD | + | 91 | AD | Microscopic DLB (insufficient for diagnosis) |
AD=Alzheimer's Disease. MCI=mild cognitive impairment. DLB=Dementia with Lewy Bodies. PD=Parkinson's Disease. PSP=progressive supranuclear palsy.