Table 2.
Echocardiography measurement in mice ~two weeks after the end of tamoxifen treatment.
| Parameters | TMCM | Pa | TMPD | TMPDPA |
|---|---|---|---|---|
| IVS;d (mm) | 0.77 ± 0.02 | 0.81 ± 0.04 | 0.95 ± 0.06* | 0.96 ± 0.02* |
| IVS;s (mm) | 1.29 ± 0.06 | 1.16 ± 0.08 | 1.30 ± 0.05 | 1.12 ± 0.05 |
| LVID;d (mm) | 3.65 ± 0.06 | 3.85 ± 0.11 | 3.91 ± 0.11 | 3.65 ± 0.09 |
| LVID;s (mm) | 2.2 ± 0.09 | 2.12 ± 0.09 | 2.54 ± 0.11* | 2.62 ± 0.09* |
| LVPW;d (mm) | 0.69 ± 0.03 | 0.67 ± 0.05 | 0.76 ± 0.04 | 0.61 ± 0.02 |
| LVPW;s (mm) | 1.13 ± 0.04 | 0.99 ± 0.06 | 1.13 ± 0.06 | 1.05 ± 0.02 |
| Ejection Fraction (%) | 71.5 ± 1.5 | 73.66 ± 1.68 | 64.71 ± 2.41* | 60.57 ± 2.31* |
| Fractional Shortening (%) | 40.1 ± 2 | 41.9 ± 1.39 | 35.01 ± 1.84* | 31.93 ± 1.59* |
| MV Decel rate (mm/s2) | −38144 ± 1666 | −30433 ± 2693 | −23192 ± 828* | −19992 ± 2873* |
| HR (Beat/Min) | 414 ± 7 | 406 ± 13 | 417 ± 25 | 390 ± 14 |
| LV mass/BW | 3.29 ± 0.13 | 3.50 ± 0.1 | 4.05 ± 0.2* | 4.05 ± 0.12* |
IVS;d and IVS;s: interventricular septum (diastole and systole); LVID;d and LVID;s: left ventricular internal diameter (diastole and systole); LVPW;d and LVPW;s: left ventricular posterior wall (diastole and systole); EF%: ejection fraction; FS%: fractional shortening. MV decal rate: mitral valve deceleration rate; HR: heart rate, LV mass/BW: ratio of left ventricular mass to body weight. *P < 0.05 versus TMCM n = 8.