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Gene duplication to the Y, out of the X and neo-X chromosomes and between autosomes, often leads (with or without the loss of the parental gene) to sex-biased expression (often male tissue-specific expression; blue). Sex-biased expression (in blue) appears to evolve often as long as the duplication involves relocation. Both RNA-mediated and DNA-mediated gene duplication appear to contribute to these effects.
