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. Author manuscript; available in PMC: 2012 Aug 3.
Published in final edited form as: Cell Metab. 2011 Aug 3;14(2):208–218. doi: 10.1016/j.cmet.2011.06.007

Figure 6. Human obesity is associated with decreased expression of RNA processing genes and can influence metabolic phenotypes.

Figure 6

Reduced expression of the splicing factor SFRS10 alters splicing of LPIN1, leading to dysregulation of lipogenic pathways and contributing to hypertriglyceridemia. Other alterations in RNA processing in human obesity should be identified (dashed arrows).