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. 2011 Jun 28;12(3):834–853. doi: 10.1208/s12249-011-9640-z

Table II.

Summary of the Ultrasonic and Physical Properties of Tablets and Roller-Compacted Ribbons

Case no. Section Tablet (n = 30) Ribbon (n = 50)
Mass density, ρ (g/cm3) Thickness, h (mm) Δt p (μs) c p (m/s) Δt p (μs) c p (m/s)
Case 1 Left 1.32 (0.005) 4.05 (0.008) 2.85 (0.08) 1,422.13 (16.11) 2.59 (0.03) 769.26 (18.14)
Middle 1.31 (0.008) 4.06 (0.014) 4.16 (0.09) 976.74 (17.76) 1.79 (0.08) 1,111.53 (17.73)
Right 1.33 (0.002) 4.05 (0.009) 3.05 (0.07) 1,328.21 (21.33) 2.40 (0.07) 833.31 (12.21)
Case 2 Left 1.31 (0.006) 4.06 (0.014) 5.12 (0.14) 793.71 (18.62) 4.40 (0.06) 454.16 (11.52)
Middle 1.32 (0.009) 4.06 (0.017) 5.12 (0.23) 794.42 (12.37) 4.22 (0.05) 473.41 (14.35)
Right 1.31 (0.011) 4.06 (0.016) 5.20 (0.22) 782.04 (20.01) 4.27 (0.08) 467.81 (4.54)
Case 3 Left 1.31 (0.005) 4.05 (0.016) 3.56 (0.09) 1,138.25 (14.28) 3.74 (0.09) 533.76 (18.27)
Middle 1.31 (0.003) 4.06 (0.008) 3.57 (0.08) 1,137.77 (13.26) 3.32 (0.10) 601.23 (41.89)
Right 1.31 (0.007) 4.06 (0.011) 3.58 (0.11) 1,135.05 (11.81) 3.65 (0.04) 547.46 (10.11)
Unlubricated 1.31 (0.012) 4.06 (0.009) 2.48 (0.04) 1,637.46 (12.78) n/a n/a
Virgin MCC powder
Lubricated 1.32 (0.009) 4.05 (0.007) 2.66 (0.05) 1,523.05 (15.99) n/a n/a
Virgin MCC powder
Virgin MCC powder (lubricated tooling) 1.31 (0.006) 4.06 (0.011) 2.53 (0.06) 1,605.54 (13.72) n/a n/a
Case 1 (blend) 1.32 (0.010) 4.06 (0.012) 3.97 (0.10) 1,021.14 (13.31) n/a n/a
Case-2 (blend) 1.31 (0.012) 4.06 (0.008) 5.17 (0.07) 785.43 (14.78) n/a n/a
Case 3 (blend) 1.32 (0.007) 4.05 (0.005) 3.55 (0.08) 1,139.67 (12.25) n/a n/a

Standard deviations in estimate of grams per cubic centimeter (for ρ), millimeters (for h), microseconds (for Δt p), and meters per second (for c p) are included in parenthesis. Tablet solid fraction of 0.85