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Model Drugs Used in the Study
| Active | Manufacturer | Average particle size (μm) | Ionic nature | Molecular weight | Log P | pKa | Solubility in water (mg/mL) |
|---|---|---|---|---|---|---|---|
| Propranolol HCl | S.I.M.S., Italy | 10 | Cationic | 295.8 | 1.2 | 9.50 | 360.0 |
| Theophylline | Sigma-Aldrich, UK | 82 | Non-ionic | 180.2 | 0.0 | 8.60 | 7.4–8.0 |
| Ibuprofen | IMCD, UK | 29 | Anionic | 206.3 | 4.0 | 4.4; 5.20 | 0.02–0.06 |
