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. 2011 Jun 28;12(3):854–861. doi: 10.1208/s12249-011-9645-7

Table II.

Dry Layer Resistance Calculated from Freeze Drying Run where Shelves are Sequentially Stoppered to Provide Sublimation Rate as a Function of Time

Thickness of dried layer, cm Rp, cm2 × Torr × h/g
0.86 4.77
1.42 5.72
2.33 7.28
2.85 7.89

This sublimation rate is then used to calculate the dry layer resistance as a function of dry layer thickness