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. 2011 Jun 28;12(3):854–861. doi: 10.1208/s12249-011-9645-7

Table V.

Effect of a 10% Change in Product Resistance Measurement on Prediction of Primary Drying Time and Product Temperature during Primary Drying

Shelf temperature, C Chamber pressure, Pa Nominal Rp 10% lower Rp 10% higher Rp
Product temperature, C
−10 10 −27 −27.4 −26.4
20 10 −17.2 −17.9 −16.3
-10 20 −23.9 −24.4 −23.5
20 20 −12.9 −13.6 −12.2
Drying time, h
−10 10 115 111 118
20 10 53 52 53.9
−10 20 94.9 91.9 97.9
20 20 41.2 40.5 41.96