Table 1. Clinical (age, sex, location, size), histological (histotype, depth infiltration in millimetre, ulceration, essudation and level of infiltration according anatomical skin layers URD upper reticular dermis; DRD deep reticular dermis ) and immunohistochemical data of 31 cases of BBC; essudation Mild=+; Moderate=++;Severe=+++; immunohistochemical score: 0= 0–6%; 1= 6–25%; 2= 25–50%; 3=51–75%;4=76–100%.

	Age	Sex	Location	Hystotype	Max.Dim	Depth	Ulc	Ess	Inf	p53	Bcl-2	Ki67	AML
1	61	M	Extr	Keratotic	10×8	1	No	+++	URD	+++	+	+	-
2	61	M	Face	Adenoid	10×9	4	No	+	URD	+++	-	-	-
3	64	M	Extr	Sup mult	11×13	0.8	No	+	DRD	+	-	-	-
4	73	M	Face	Nodular	10×8	2	Yes	+	DRD	+++	+	++	+++
5	84	M	Face	Nodular	9×12	2	Yes	+	DRD	-	-	-	-
6	84	M	Face	Adenoid	5	0.8	No	+	URD	+++	-	-	-
7	84	M	Extr	Nodular	13×10	3	No	+	DRD	+++	+	+	-
8	52	F	Face	Nodular	4	0.8	No	+	URD	+	+	+	-
9	76	F	Face	Adenoid	10×4	4	No	+	DRD	+++	-	++	-
10	77	F	Face	Morph	8×6	1	Yes	+++	DRD	+++	-	-	-
11	86	M	Face	Morph	8	1	Yes	+	DRD	+++	-	+	+
12	63	F	Face	Adenoid	4	1	No	+	URD	++	+	+	+
13	76	F	Face	Nodular	7	1.5	No	+	DRD	+++	+	++	-
14	84	M	Face	Nodular	11	4	Yes	+++	DRD	+	-	-	+
15	63	F	Face	Keratotic	10×6	1.8	No	++	DRD	-	+	++	-
16	68	F	Trunk	Sup mult	10×6	0.7	No	++	URD	+	+	-	-
17	67	M	Face	Sup mult	12×6	0.4	No	+	URD	+	-	+	-
18	67	M	Extr	Sup mult	4×3	0.3	No	+	URD	+	+++	+	-
19	32	F	Extr	Sup mult	1×3	0.4	No	+	URD	+	+	+	-
20	45	M	Trunk	Nodular	7×5	2	Yes	+++	URD	+	+	+	-
21	62	M	Trunk	Sup mult	11×7	0.9	No	++	URD	-	++	-	++
22	65	M	Trunk	Adenoid	7×6	1.5	No	+	URD	+++	+	+	-
23	72	M	Trunk	Nodular	12×6	1	No	+	URD	+++	-	+	+
24	86	F	Face	Keratotic	20×11	3.1	No	++	DRD	+	+	+	-
25	85	M	Face	Nodular	0.5	1.3	No	++	DRD	++	+	+	-
26	74	F	Extr	Nodular	4×4	0.9	No	+	URD	-	-	+	-
27	71	M	Face	Nodular	6×12	1.7	No	+	DRD	-	-	+	-
28	64	F	Trunk	Sup mult	1.3×1.5	0.4	No	++	URD	+++	-	-	-
29	78	F	Face	Nodular	4×3	1.5	No	++	DRD	++	+	-	+++
30	80	M	Face	Keratotic	4×4	1.6	Yes	+	DRD	-	-	+	+++