Table 2.

DXA measurements of BMC in adult mice

		Wild type (n = 6)	TRα1−/−β−/− (n = 6)	Difference (%)a
Total body	bone mineral density (mg/cm2)	68.2 ± 5.2	67.0 ± 4.8	−1.7
	bone area (cm2)	11.8 ± 1.8	10.6 ± 1.0	−9.7
	BMC (mg)	761 ± 69	689 ± 29	−9.5
Femur	Bone mineral density (mg/cm2)	62.2 ± 1.6	63.2 ± 0.8	1.6
	Bone area (cm2)	0.517 ± 0.010	0.418 ± 0.008	−19.0**
	BMC (mg)	32.2 ± 1.2	26.5 ± 0.8	−18.0**
Tibia	Bone mineral density (mg/cm2)	57.3 ± 1.4	54.2 ± 0.6	−5.5
	Bone area (cm2)	0.435 ± 0.010	0.397 ± 0.006	−8.8**
	BMC (mg)	25.0 ± 1.1	21.5 ± 0.5	−14.0*
Vertebrae L6	Bone mineral density (mg/cm2)	61.8 ± 0.7	64.7 ± 0.9	4.6
	Bone area (cm2)	0.132 ± 0.004	0.100 ± 0.004	−24.0**
	BMC (mg)	8.15 ± 0.22	6.47 ± 0.28	−21.0**

^a(*) P < 0.05; (**) P < 0.01 vs. wild type; no asterisk indicates no significant difference (P > 0.05); determined by Student’s t-test.