. Author manuscript; available in PMC: 2011 Sep 6.

Published in final edited form as: Gastroenterology. 2009 Mar 6;136(7):2304–2315.e1-4. doi: 10.1053/j.gastro.2009.02.067

Table 2.

Altered gene expression in Albumin-Cre;Dicer1^loxP/loxP mouse liver

Genes related to Cell division			Genes related to Steroid synthesis

Gene name	Microarray	qPCR	Gene name	Microarray	qPCR
Aurka	2.8^*	4.0^*	Dhcr7^#	0.30^*	0.29^*
Aurkb	2.2, 2.5^*	3.5^*	Fdft1^#	0.21^, 0.28^	0.37^*
Ccna2	2.4^, 2.6^	3.7^*	Fdps^#	0.066^*	0.09^*
Ccnb1	2.8^, 3.0^	4.0^*	Hmgcr	0,36, 0.39 0.18^, 0.22^	0.29
Ccnb2	3.0^*	4.0^*	Hmgcs1^#	0.22^, 0.29^	0.37^*
Ccnd1	2.8^, 3.1^, 3.1^*	3.8^*	Hsd17b7	0.35^*	0.51
Ccng1^#	2.2^*	2.3^*	Mvk^#	0.14^, 0.34^	0.34
E2f5	0.7, 1.5, 2.0^*	2.4^*	Pmvk	0.14^*	0.25^*
Plk1	3.6^*	5.2^*	Tm7sf2	0.28^*	0.27^*

Gene expression levels of 3-week-old Albumin-Cre;Dicer1^loxP/loxP mouse livers analyzed by cDNA microarray (n=3, each group), and the results were further confirmed by quantitative PCR (qPCR; n=4, each group). Values are indicated as fold changes compared with control mouse livers.

Significantly altered genes in mir-122 knockdown study ^{4, 5};

: Genes with significantly altered expression. FDR<0.05 for microarray and P<0.05 for qPCR.