Table 2.

Properties of several BMPs. The resistance to noggin is caused by a lysine residue at position 60 in the molecule. Also the ability to induce differentiation in pluripotent and preosteoblastic cells is described. The possible induction of mineralised matrix by the different BMPs is described. The potency of superior BMPs with reference to less potent BMPs is explained

	BMP-2	BMP-6	BMP-7	BMP-9
Resistance to noggin	No [18, 19]	Yes [19]	No [19]	Yes [18, 19]
Inducing differentiation in stem cells [17]	Notable increase in induction	Notable increase in induction	Detectable, but marginal induction	Notable increase in induction
Inducing differentiation in preosteoblastic cells [17]	Marked increase in induction	Marked increase in induction	Increase of induction at later time point	Marked increase in induction
Induction of mineralised matrix [17]	Readily detectable nodules	Readily detectable nodules	Sparse, but detectable nodules	Readily detectable nodules
Specific BMP more potent than other BMPs		More potent than BMP-2 [62]		Higher induction of expression with specific molecules than BMP-2 [66]