Table 11a.
Association between formaldehyde and Hodgkin's lymphoma (ICD 201).
| Beane Freeman et al., 2009 | Andjelkovich et al., 1995 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| NCI cohort (1934–2004) | Iron foundry workers | |||||||||
| Measures | Category | Obs | Estimate | 95% CI | Category | Obs | Estimate | 95% CI | ||
| Unexposed/Exposed | Unexposed | 2 | SMR | 0.70 | 0.17–2.80 | Unexposed | 0 | SMR | 0.00 | 0.00–4.12 |
| Exposed | 25 | SMR | 1.42 | 0.96–2.10 | Exposed | 1 | SMR | 0.72 | 0.01–4.00 | |
| Peak Exposure | 0 ppm | 2 | RR | 0.67 | 0.12–3.60 | |||||
| >0–<2.0 ppm | 6 | RR | 1.00 | — | ||||||
| 2.0–<4.0 ppm | 8 | RR | 3.30 | 1.04–10.50 | ||||||
| ≥4.0 ppm | 11 | RR | 3.96 | 1.31.12.02 | ||||||
| ptrend = .01 (exposed) | ||||||||||
| ptrend = .004 (exposed and unexposed) | ||||||||||
| Average Intensity | 0 ppm | 2 | RR | 0.53 | 0.11–2.66 | |||||
| >0–<0.5 ppm | 10 | RR | 1.00 | — | ||||||
| 0.5–<1.0 ppm | 9 | RR | 3.62 | 1.41–9.31 | ||||||
| ≥1.0 ppm | 6 | RR | 2.48 | 0.84.7.32 | ||||||
| ptrend = .05 (exposed) | ||||||||||
| ptrend = .03 (exposed and unexposed) | ||||||||||
| Cumulative Exposure | 0 ppm-yr | 2 | RR | 0.42 | 0.09–2.05 | |||||
| >0–<1.5 ppm-yr | 14 | RR | 1.00 | — | ||||||
| >1.5–<5.5 ppm-yr | 7 | RR | 1.71 | 0.66–4.38 | ||||||
| >5.5 ppm-yr | 4 | RR | 1.30 | 0.4.4.19 | ||||||
| ptrend = .08 (exposed) | ||||||||||
| ptrend = .06 (exposed and unexposed) | ||||||||||
| Cumulative number of peaks ≥4.0 ppm | No association. Results not shown. | |||||||||
| Duration of Employment | No association. Results not shown. | |||||||||