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. 2011 Jun 2;41(7):555–621. doi: 10.3109/10408444.2011.560140

Table 13a.

Association between formaldehyde and multiple myeloma (ICD 203).

Beane Freeman et al., 2009

NCI cohort (1934-2004)

Measures Category Obs Estimate 95% CI
Unexposed/eEposed Unexposed 11 SMR 1.78 0.99–3.22
Exposed 48 SMR 0.94 0.71–1.25
Peak Exposure 0 ppm 11 RR 2.74 1.18–6.37
>0–<2.0 ppm 14 RR 1.00
2.0–<4.0 ppm 13 RR 1.65 0.76–3.61
≥4.0 ppm 21 RR 2.04 1.01.4.12
ptrend = .08 (exposed)
ptrend > .5 (exposed and unexposed)
Average Intensity 0 ppm 11 RR 2.18 1.01–4.70
>0–<0.5 ppm 25 RR 1.00 —
0.5–<1.0 ppm 11 RR 1.40 0.68–2.86
>1.0 ppm 12 RR 1.49 0.73.3.04
ptrend > .5 (exposed)
ptrend > .5 (exposed and unexposed)
Cumulative Exposure 0 ppm-yr 11 RR 1.79 0.83–3.89
>0–<1.5 ppm-yr 28 RR 1.00
>1.5–<5.5 ppm-yr 5 RR 0.46 0.18–1.20
≥5.5 ppm-yr 15 RR 1.28 0.67.2.44
ptrend > .5 (exposed)
ptrend > .5 (exposed and unexposed)
Cumulative number of peaks ≥4.0 ppm No association. Results not shown.
Duration of Employment No association. Results not shown.